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GLYCOGEN SYNTHASE KINASE 3 BETA
Descriptors Found:
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DeCS
Descriptor
English
:
Glycogen Synthase Kinase 3 beta
Descriptor
Spanish
:
Glucógeno Sintasa Quinasa 3 beta
Descriptor
Portuguese
:
Glicogênio Sintase Quinase 3 beta
Synonyms
English
:
GSK-3beta
GSK3B Protein
GSK3beta
GSK 3beta
Tree Number:
D05.500.117.875.500
D08.811.913.696.620.682.700.429.500.500
D08.811.913.696.620.682.700.646.625.500
D12.644.360.300.500.500
D12.776.476.081.875.500
D12.776.476.300.500.500
Definition
English
:
A
glycogen synthase
kinase-3 type enzyme that functions in
ENERGY METABOLISM
;
EMBRYONIC DEVELOPMENT
; and
NEUROGENESIS
. It is also involved in
PROTEIN BIOSYNTHESIS
and regulates cell
growth
and proliferation as a component of the
WNT SIGNALING PATHWAY
and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with
PARKINSON DISEASE
;
ALZHEIMER DISEASE
; and
BIPOLAR DISORDER.
History Note
English
:
2017 (2002)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56432
Unique Identifier:
D000071679
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS